Eltrombopag: SB-497115-GR is a thrombopoietin receptor agonist. TREPTORA: Eltrombopag is indicated for the treatment of Immune Thrombocytopenic Purpura (ITP). TREPTORA is a generic manufactured by Genvio Pharma Limited. Genvio is one of the top anti-cancer medicine manufacturers in Bangladesh. It is dedicated to manufacture quality medicine at an affordable price compared to the cost of PROMACTA manufactured by NOVARTIS.
TREPTORA: Eltrombopag 25 mg and 50 mg both are available in 28’s pack size. TREPTORA is available for both local and global market.
TREPTORA: Generic of PROMACTA is designated for the treatment of thrombocytopenia in adult and pediatric patients 1 year. And older patients with Chronic Immune Thrombocytopenia who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy.
TREPTORA is also indicated for-Treatment of Thrombocytopenia in Patients with Hepatitis C Infection In combination with standard immunosuppressive therapy for the first-line treatment severe aplastic anemia. Also in severe aplastic anemia those have had an insufficient response to immunosuppressive therapy. Limitations of Use: Eltrombopag: SB-497115-GR is not indicated for the treatment of patients with myelodysplastic syndrome (MDS). Safety and efficacy have not been established in combination with direct-acting antiviral agents used without interferon for treatment of chronic hepatitis C infection. TREPTORA the generic of PROMACTA has some common side effects: Nausea,diarrhea, upper respiratory tract infection (symptoms may include runny nose, stuffy nose, and sneezing), vomiting, urinary tract infection, pain or swelling (inflammation) in your throat or mouth (oropharyngeal pain and pharyngitis), abnormal liver function tests, muscle aches. Eltrombopag: SB-497115-GR is an orally bioavailable, small-molecule TPO-receptor agonist that interacts with the transmembrane domain of the human TPO-receptor and initiates signaling cascades that induce proliferation and differentiation from bone marrow progenitor cells. Genvio Pharma Limited is manufacturing and supplying TREPTORA: Eltrombopag in a low cost than the originator brand PROMACTA manufactured by NOVARTIS. Genvio Pharma Limited is offering the oral solid Eltrombopag. Which is much more convenient to take and transport all over the country. Each TREPTORA box contains patient medication information leaflet. So before starting medication please go through the leaflet or download easily from website of TREPTORA. Kindly visit: https://treptora.com/prescribing-information/ Dosage and administration system of Eltrombopag: SB-497115-GR is slightly complicated. TREPTORA: Eltrombopag can be taken on an empty stomach: 1 hour before or 2 hours after a meal. Chronic ITP: Initiate TREPTORA at 50 mg once daily for most adult and pediatric patients 6 years and older patient. And 25 mg once daily for pediatric patients aged 1 to 5 years. Chronic Hepatitis C-associated Thrombocytopenia: Initiate TREPTORA at 25 mg once daily for all patients. First-line Severe Aplastic Anemia: Initiate TREPTORA once daily at 2.5 mg/kg (in pediatric patients aged 2 to 5 years old), 75 mg (pediatric patients aged 6 to 11 years old), or 150 mg for patients aged 12 years and older concurrently with standard immunosuppressive therapy. Refractory Severe Aplastic Anemia: Initiate TREPTORA at 50 mg once daily. The most common side effects when TREPTORA: Eltrombopag is used in combination with other medicines to treat chronic HCV are: Low red blood cell count (anemia), fever, tiredness, headache, nausea, diarrhea, decreased appetite, flu-like symptoms including fever, headache, tiredness, cough, sore throat, and body aches, trouble sleeping, feeling weak, cough, itching, chills, muscle aches, hair loss, swelling in your ankles, feet, and legs. The most common side effects when Eltrombopag: SB-497115-GR is used to treat SAA when other medicines to treat SAA have not worked well enough: Nausea, feeling tired, cough, diarrhea, headache. Before taking TREPTORA the generic of PROMACTA, anyone should ask their health care provider if anyone has: liver problems precancerous condition called MDS or a blood cancer had a blood clot a history of cataracts had surgery to remove the spleen (splenectomy) bleeding problems is pregnant or plan to become pregnant. It is not known if Eltrombopag will harm an unborn baby. Ask health care provider if you become pregnant or think you may be pregnant during treatment with Eltrombopag. For woman who is able to become pregnant, you must use reliable birth control while taking Eltrombopag and for at least 7 days after you stop taking Eltrombopag. Ask health care provider about options of effective birth control methods that may be right for you during this time You can also check out the full patient leaflet of originator brand PROMACTA (https://www.us.promacta.com/) Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count with an unknown cause. As most reasons appear to be related to antibodies against platelets. It is also known as immune thrombocytopenic purpura. The normal platelet level in adults is between 150,000 and 450,000/mm3. When the platelet counts below 50,000 mm3 it increases the risk of hazardous bleeding from trauma; counts below 20,000/mm3 increase the risk of spontaneous bleeding. Idiopathic thrombocytopenic purpura may be either acute or chronic. The incidence of ITP is 50-100 new cases per million per year. Where children accounting for half of that amount and the median age of adults at the diagnosis is 56-60. In adults, ITP is considered an autoimmune disorder, which means that the body produces antibodies that damage some of its own products-in this case, blood platelets. To learn more about ITP: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147825/ Genvio Pharma Limited, a renowned pharmaceutical company in Bangladesh is manufacturing TREPTORA, the generic of Eltrombopag and providing a quality product at an affordable price to the patients both locally and globally. Genvio Pharma Limited has aimed to provide quality medicine at a reasonable cost that patient can fight against autoimmune diseases like thrombocytopenia and can maintain a healthy life. Genvio Pharma Limited takes pride in manufacturing quality medicine by adhering to the current Good Manufacturing Practice to meet the international standard. Being one of the top anti-cancer medicine manufacturers in Bangladesh, Genvio Pharma Limited is committed to manufacture better alternatives of research molecules at an affordable price. So Genvio is keeping the cost of new generic TREPTORA comparatively lower than the cost of PROMACTA for the patient who cannot afford PROMACTA treatment.